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Stage 1: Getting Started: Step 1: How to Formulate a Research Question

Formulating your Research Question

The research question is truly the heart of a synthesis review. From the type of synthesis review chosen to the type of data analysis conducted, the research question is essential to guiding each stage of the review.

In this step, your goal is to establish a research question that is:​

  • Specific and focused
  • Answerable/testable
  • A novel and meaningful contribution to the literature

Use a Tool to Create a Focused Research Question

Identifying the concepts that you are interested in will help you compose and focus your research question. These concepts can be identified using a variety of question formats (e.g., PICO[T], PIE, SPIDER, ECLIPSE).

Below is a list of the commonly used (but not exhaustive) question formats to help structure your research question. For more information, scroll to the Additional Resources at the bottom of this page.

PICO/PECO

The PICO/PECO structure is often used in the health sciences to research prognoses, diagnoses, and therapies. It is useful for comparing one intervention with another.

Example Question
(provided by Des Moines University Library)

Does hand washing among healthcare workers reduce hospital acquired infections?

This search framework can include PICOT and PICOS which are frameworks which accommodate for the concepts of Time and Study design, respectively.

Examples of other Search Frameworks: