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Clinical Medicine: Critical Appraisal

Checklists & Tools

Cochrane Collaboration Risk of Bias Tools

Cochrane Handbook for Systematic Reviews of Interventions - Chapter 8

Higgins, J. P., Altman, D. G., Gøtzsche, P. C., Jüni, P., Moher, D., Oxman, A. D., ... & Sterne, J. A. (2011). The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ: British Medical Journal, 343.

CASP UK (Critical Appraisal Skills Program)

Critical appraisal checklists for randomized controlled trials, systematic reviews, cohort studies, case control studies, qualitative research, economic evaluations, diagnostic tests, clinical prediction rules


Joanna Briggs Institute Critical Appraisal Tools

In Pearson, A., Field, J., & Jordan, Z. (2009). Evidence-based clinical practice in nursing and health care: assimilating research, experience and expertise.  Appendix 2.         Located in the Health Sciences Library RT42 .P43 2007

GRADE Guidelines.

Guyatt, G. H., Oxman, A. D., Vist, G., Kunz, R., Brozek, J., Alonso-Coello, P., ... & Schünemann, H. J. (2011). GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias). Journal of clinical epidemiology, 64(4), 407-415.

Centre for Evidence Based Medicine

Critical Appraisal Worksheets


Learning Critical Appraisal Skills

Listed below are a few resources that may be helpful in learning how to critically appraise an article.